The present invention provides methods and compositions for treating arteriosclerotic vascular diseases by pharmaceutical compositions comprising a component of at least one species from the genus Sargassum a component of at least one species from the genus Lonicera and a component of at least one species from the genus Cimicifuga.本發明提供藉包含得自馬尾藻(Sargassum)屬中之至少一種的一成分;得自忍冬(Lonicera)屬中之至少一種的一成分;及得自升麻(Cimicifuga)屬中之至少一種的一成分的藥學組成物用於治療動脈硬化性血管病變之方法及組成物。