David A. Eavarone,Jeffrey Behrens,Alexey Alexandrovich Lugovskoy
申请号：
US16462075
公开号：
US20190276541A1
申请日:
2017.11.17
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present disclosure provides antibodies with T cell-interacting regions and/or glycan-interacting regions. Bispecific antibodies capable of recruiting T cells to cancer cells are also provided, including bispecific antibodies capable of recruiting T cells to cancer cells expressing sialyl Tn (STn). The present disclosure also includes methods for killing cells by targeting them with antibodies having T cell-interacting regions.
