Methods and devices are used to treat a dorsal vein to reduce blood flow in patients suffering from erectile dysfunction. For example, a clip may be advanced distally across the deep dorsal vein and an anchor on the clip deployed on a proximal side of the Tunica albuginea. The clip can then be pulled back and a distal anchor on the clip deployed to reduce a cross-sectional area of the deep dorsal vein and anchor the deep dorsal vein to the Tunica albuginea. Anchoring of the dorsal vein to the Tunica albuginea further reduces the cross-sectional area of the deep dorsal vein in response to expansion of the patient's corpora cavernosa.
