PROCÉDÉ D'IMAGERIE PAR RÉSONANCE MAGNÉTIQUE POUR DÉTERMINER DES INDICES DE SIGNATURE D'UN TISSU OBSERVÉ À PARTIR DE MODÈLES DE SIGNAUX OBTENUS PAR IMPULSION DE GRADIENT DE CHAMP MAGNÉTIQUE VARIABLE
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
发明人:
申请号:
EP15305546.2
公开号:
EP3081955A1
申请日:
2015.04.13
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
A method for determining a signature index of an observed tissue comprises the step of providing (12) a generic attenuation model of a motion-probing gradient pulse MRI attenuated signal S(b), and providing (14) a reference model parameter vector (pR(i)) corresponding to a reference state of the tissue.On the basis of the evolution of the determined (16) partial differential sensitivities dS¡(b) of the model attenuated signal S(b) to each model parameter p(i) at the neutral state attenuated signal SN(b) versus b values, a discrete and narrow size set of key b is built (18) and a series of MRI images of the observed tissue are acquired (20) by using the key b values.Then, for each voxel a signature index (sADC(V), Sdist(V), SCdist(V), Snl(V), SI(V)) of the voxel V is determined (22) as a scalar function depending on a distance between the voxel signal pattern acquired at the key b values and the signal pattern of the reference state of the tissue at the same key b values.An apparatus is configured for implementing such a method.