OLIGONUCLEOTIDE BISPECIFIQUE POUR LE TRAITEMENT DES MALIGNITES DU SYSTEME NERVEUX CENTRAL

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专利权人:

THE UNIVERSITY OF BRITISH COLUMBIA

发明人:

申请号：

EP04786690.0

公开号：

EP1667731B1

申请日:

2004.09.30

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

CNS malignancy is treated in a subject suffering from a CNS malignancy by administering to the subject an antisense oligonucleotide having a sequence of bases that is complementary to portions of both the gene encoding IGFBP-2 and the gene encoding IGFBP-5, and which is of sufficient length to act as an inhibitor of the effective amount of IGFBP-2 and IGFBP-5, in an amount effective to reduce effective levels of IGFBP-2 and IGFBP-5 in cells of the CNS malignancy.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/