Catherine Moorwood;Tejvir S. Khurana;Olga Lozynska;Neha Suri;Scott L. Diamond;Andrew D. Napper;Emidio Pistilli
发明人:
Tejvir S. Khurana,Scott L. Diamond,Catherine Moorwood,Olga Lozynska,Andrew D. Napper,Emidio Pistilli,Neha Suri
申请号:
US13129074
公开号:
US20120010176A1
申请日:
2009.11.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Methods are provided for increasing utrophin promoter activity, utrophin expression or utrophin activity, and treating or reducing the symptoms of muscular dystrophy by administering to a subject in need thereof an effective amount of a composition comprising a utrophin promoter or activity upregulator. Muscular dystrophy includes but is not limited to Duchenne muscular dystrophy, Becker's muscular dystrophy, limb girdle muscular dystrophy, or a disease characterized by mutation or dysregulation of the dystrophin gene or an aberrant or dysfunctional dystrophin.