This invention provides systems and methods for arresting, treating and/or preventing diseases caused by amyloid deposits of proteins. This invention teaches procedures and therapeutic compositions for controlling amyloids and related plaque deposits. This invention is applicable to common diseases including, but not limited to: Alzheimers, cardiovascular, stroke, arterial sclerosis, etc. By addressing plaque development at the earliest stages involving protein-protein interaction, plaque growth is decreased or eliminated and the balance of plaque deposition/management is switched to favor the bodys natural aberrant protein removal mechanisms. The invention also simple provides procedures and/or kits for effective analysis to achieve earliest detection. Analysis may be undertaken in a clinical setting, but the present invention provides systems and methods for obtaining the relevant information in person by the patient or by an associate with no clinical training required.