Joachim P. SPATZ,Fania GEIGER,Michael THALLER,Christian LINGENFELDER,Heike BOEHM
申请号:
US15741717
公开号:
US20180193535A1
申请日:
2016.07.06
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to an ocular device for regulating intraocular fluid pressure comprising or consisting of a tubular body wherein the inner surface of the tubular body or the inner and outer surface is/are coated with covalently immobilized hyaluronic acid (HA). In more specific embodiments, the tubular body comprises or consists of a biocompatible material selected from the group comprising a biocompatible metal such as titanium, ceramics, glass, polymers and composites thereof, and the immobilized hyaluronic acid molecules are linked with further HA molecules to form a HA hydrogel. The ocular device is a stent free from mechanical valves or other mechanical means for actively regulating the flow of intraocular fluid.