The present invention relates to compounds (I) capable of inhibiting the Mst1/2 protein kinase activity, a preparation method therefor, a pharmaceutical composition comprising the compounds, and uses of the compounds and the pharmaceutical composition comprising the compounds in the preparation of drugs for prompting repair and regeneration of tissues and organs, prompting stem cell proliferation and adult cell dedifferentiation, immunosuppression, and preventing or treating diseases related to nervous disorders in organisms, and local ischemia diseases.本發明涉及一類具有抑制Mst1/2蛋白激酶活性的化合物,其製備方法、包含該化合物的藥物組合物,以及這些化合物及包含該化合物的藥物組合物在製備用於促進組織和器官的再生與修復,促進幹細胞增殖和成體細胞去分化,免疫抑制,預防或治療與生物體內神經紊亂相關疾病和局部缺血的疾病藥物中的用途:。
