アルツハイマー病の予防及び治療薬並びにアルツハイマー病の予防及び治療薬のスクリーニング方法
- 专利权人:
- 公益財団法人ヒューマンサイエンス振興財団
- 发明人:
- 道川 誠,西辻 和親
- 申请号:
- JP2009289487
- 公开号:
- JP5629896B2
- 申请日:
- 2009.12.21
- 申请国别(地区):
- JP
- 年份:
- 2014
- 代理人:
- 摘要:
PROBLEM TO BE SOLVED: To provide a preventive and therapeutic agent for Alzheimers disease, which tremendously improve efficiency of A&beta decomposition in the brain to remarkably suppress the development and progress of Alzheimers disease.
SOLUTION: The preventive and therapeutic agent for Alzheimers disease includes lipoprotein lipase (LPL) as an active ingredient. The preventive and therapeutic agent for Alzheimers disease is administered in the brain, whereby the LPL promotes inclusion of A&beta into cells of microglia, astrocyte, or the like in the brain, and the included A&beta is decomposed rapidly in the cells, so that the efficiency of A&beta decomposition in the brain is tremendously improved, and accumulation of the A&beta in the brain is remarkably suppressed.
COPYRIGHT: (C)2011,JPO&INPIT
- 来源网站:
- 中国工程科技知识中心
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