Industry Academic Cooperation Foundation; Hallym University
发明人:
Hyung Joo KWON,Yong Sung KIM
申请号：
US16313695
公开号：
US20190231872A1
申请日:
2017.07.11
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to a vaccine composition comprising cyclic peptides of the present invention, antibodies to cyclic peptides, or an anticancer composition comprising them, and the vaccine composition of the present invention exhibit an inhibitory activity for metastasis of cancer. In addition, the antibodies of the present invention bind to the tumor-specific antigen TM4SF5 with high affinity, and significantly inhibit the growth, metastasis and invasion of cancer cells expressing the tumor-specific antigen TM4SF5, and thus can be used for diagnosis, prevention or treatment of various cancers expressing TM4SF5.
