A microparticle for cell encapsulation is provided, having a core which comprises continuous fibers of decellularized extracellular matrix (ECM) and, optionally, an outer layer. Also provided are methods of encapsulating cells in the microparticle, pharmaceutical compositions comprising the microparticle, and methods of treating disease in animals employing the microparticles of the invention, for example, treating Diabetes.L'invention concerne une microparticule destinée à l'encapsulation de cellules, présentant un noyau qui comprend des fibres continues de matrice extracellulaire (MEC) décellularisée.
