David M. Collard;Catherine D. Reyes;Timothy Petrie;Abigail M. Wojtowicz;Barbara D. Boyan;Jenny E. Raynor;Zvi Schwartz;Andres J. Garcia;Robert E. Guldberg
发明人:
Andres J. Garcia,Catherine D. Reyes,Timothy Petrie,Zvi Schwartz,Barbara D. Boyan,Jenny E. Raynor,David M. Collard,Abigail M. Wojtowicz,Robert E. Guldberg
申请号：
US13372234
公开号：
US20120142597A1
申请日:
2012.02.13
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Methods and compositions are provided for improving tissue growth and device integration in vivo. Substrates and devices coated with an α2β1 or α5β1 integrin-specific ligand are provided. The substrates and devices coated with an α2β1 or α5β1 integrin-specific ligand are shown to have greater tissue formation on the surface relative to controls, in particular greater bone formation.
