chemical entities, pharmaceutical compositions, pharmaceutically acceptable compounds or salts thereof, uses of chemical entities or compositions and methods for treating diseases, disorders or medical conditions mediated by pde1 enzymatic activity and for modulating pde1 enzyme activity
Andrew Richard HUDSON,Brian DYCK,Bryan BRANSTETTER,James BREITENBUCHER,Laurent GOMEZ,Marco PETERS,Tami Jo MARRONE,Troy VICKERS
申请号：
BR112014031730
公开号：
BR112014031730A2
申请日:
2013.06.18
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
"Chemical entities, pharmaceutical compositions, pharmaceutically acceptable compounds or salts thereof, uses of chemical entities or compositions and methods for treating diseases, disorders or medical conditions mediated by pde1 enzyme activity and for modulating pde1 enzyme activity" summary are described herein compounds and chemical entities of formula (I), methods of synthesizing them, compositions comprising them and their use in the treatment of various diseases and disorders, including cognitive deficits associated with snc diseases and disorders. 1/1“entidades químicas, composições farmacêuticas, compostos ou sais farmaceuticamente aceitáveis dos mesmos, usos de entidades químicas ou composições e métodos para tratar doenças, distúrbios ou condições médicas mediadas pela atividade enzimática de pde1 e para modular a atividade da enzima pde1” resumo são descritos aqui compostos e entidades químicas da fórmula (i), métodos de síntese dos mesmos, composições que compreendem os mesmos e seu uso no tratamento de várias doenças e distúrbios, incluindo déficits cognitivos associados a doenças e distúrbios do snc. 1/1
