A surgical stapling system is disclosed. The system comprises a distal end, an unspent staple cartridge comprising a plurality of staples removably stored therein, a channel configured to receive the unspent staple cartridge, and an anvil configured to deform said staples. The system further comprises a firing drive movable through a firing stroke and a primary lockout configured to prevent the firing member from being moved through the firing stroke if the unspent staple cartridge is not positioned in the channel. The system further comprises a secondary lockout actuatable to prevent the firing member from being moved through the firing stroke, wherein the secondary lockout is actuated in response to the firing stroke being prevented by the primary lockout.