Provided herein is a compound having Formula (I), or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, which can be used for treating HCV infection or a HCV disorder. Also provided herein are pharmaceutical compositions comprising the compounds disclosed herein, which can be used for treating HCV infection or a HCV disorder.本發明提供一些如式(I)所示的橋環化合物或其立體異構體,幾何異構體,互變異構體,氮氧化物,水合物,溶劑化物,代謝產物,藥學上可接受的鹽或前藥,用於治療丙型肝炎病毒(HCV)感染或丙型肝炎疾病。本發明還公開了含有這樣的化合物的藥物組合物和本發明化合物或其藥物組合物在製備用於治療HCV感染或丙型肝炎疾病的藥物中的用途。
