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Pyrimidine, pyridine and triazine derivatives as maxi-K channel openers
专利权人:
Yasuyuki Tsuzuki;Miki Hirai
发明人:
Yasuyuki Tsuzuki,Miki Hirai
申请号:
US12936987
公开号:
US08575338B2
申请日:
2009.04.08
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A compound of formula (A); wherein ring A is an aromatic ring or a heteroaromatic ring; R1 is independently halogen, cyano, etc., each of X1, X2 and X3 is CR2 or nitrogen, R2 is independently hydrogens, etc., n is 0, 1, 2, 3 or 4; -D-Y is —O—CH2COOH, etc, and G is a substituted amino, a substituted heterocyclic group, etc, or a pharmaceutical acceptable salt thereof, has activities of opening BK channels.
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