Michael J. Sailor,Sangeeta N. Bhatia,Ji-Ho Park,Geoffrey A. Von Maltzahn
申请号:
US13219906
公开号:
US20120059240A1
申请日:
2011.08.29
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The disclosure provides a long-circulating, micellar hybrid nanoparticles (MHN) that contain MN, QD, and the anti-cancer drug doxorubicin (DOX) within a single polyethylene glycol (PEG)-phospholipid micelle and provide the first examples of simultaneous targeted drug delivery and dual-mode NIR-fluorescent and MR imaging of diseased tissue in vitro and in vivo.