Inc.;H. Lee Moffitt Cancer Center and Research Institute
发明人:
Scott Antonia,Alberto Chiappori
申请号：
US15563847
公开号：
US20180078628A1
申请日:
2016.04.04
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A method is disclosed for treating small cell lung cancer (SCLC) in a subject that involves administering to the subject a therapeutically effective amount of dendritic cells engineered to overexpress p53. In some embodiments, the method further involves administering to the subject a therapeutically effective amount of all-trans-retinoic acid (ATRA). The method can also involve administering to the subject a therapeutically effective amount of an immune checkpoint inhibitor.
