Dong-Hwa Shon,Hee-Soon Shin,Min-Jung Bae,Ok-Hee Chai,Chang-Yuil Kang,Dae-Woon Choi,Gye-Young Choi,Jeong-Hae Rho,Jeong-Ryong Do
申请号：
US14404631
公开号：
US10016475B2
申请日:
2013.05.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides a composition for preventing, improving, or treating Th1-mediated immune diseases or Th2-mediated immune diseases, an antihistamine composition, and an anti-inflammatory composition. The present invention provides a method for preventing, improving, or treating Th1-mediated immune diseases or Th2-mediated immune diseases, a method for inhibiting the release of histamine, and a method for preventing, improving, or treating inflammatory disorders. The composition according to the present invention has excellent inhibitory activities for IL-4 generation, the degranulation of mast cells, COX-2, 15-NOX, and the passing of allergens from through an intestinal epithelial cell layer, or an excellent Treg cell inducing activity. Further, the present invention provides a detailed mechanism of action of a natural substance and a food-drived antiallergenic substance, and provides stability, a reduction in production costs, and improved convenience of use by using a natural substance as a material.
