Provided is a disposable safety infusion device having a sealing piece unlikely to come off and having good sealing. Also provided is a disposable safety infusion device having a self-destruction function. The disposable safety infusion device comprises a bottle insertion needle (110), a dropper (111), a hose (112), a medicinal liquid filter (113) and an intravenous infusion needle (114) all sequentially disposed and in communication with each other a flow regulator (115) for controlling the flow rate is sleeved outside the hose (112). The disposable safety infusion device further comprises a safety valve mechanism having a mechanical flow control function and disposed in the dropper (111) or between the hoses (112) the safety valve mechanism comprises a casing (II102), and a floating main piece (106) disposed inside the casing (II102) and having a cavity therein the lower face of the floating main piece (106) is connected to a sealing piece (105) the lower end of the casing (II102) is provided with an infusion channel port (109) the infusion channel port (109) is located below the sealing piece (105). The disposable safety infusion device is also provided with a structure for balancing the air pressure inside and outside the floating main piece (106) during vacuum sterilization treatment of the safety infusion device.Linvention concerne un dispositif de perfusion de sécurité jetable, ayant une pièce de scellement étanche ayant peu de risque de se détacher et ayant une bonne étanchéité. Linvention concerne également un dispositif de perfusion de sécurité jetable ayant une fonction dautodestruction. Le dispositif de perfusion de sécurité jetable comprend une aiguille dintroduction dans une bouteille (110), un compte-gouttes (111), un tuyau souple (112), un filtre de liquide médicinal (113) et une aiguille de perfusion intraveineuse (114), tous disposés de façon séquentielle et en communication les uns avec les autres un régulateur découlement (115) pour commander le
