Luis Mauricio TRAMBAIOLI DA ROCHA E LIMA,Luiz Henrique GUERREIRO ROSADO,Mariana Fernandes de AVILA NETTO GUTERRES,Bruno MELO VIEIRA GONÇALVES FERREIRA
申请号：
US14968033
公开号：
US20160184401A1
申请日:
2015.12.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present disclosure concerns new non-agglomerating bioconjugates of amylin, amylin-mimetic compounds, and combinations comprising the same. Methodology of making and using are provided herein. In some embodiments, an instant non-agglomerating amylin bioconjugate can be used for treating a disease associated with a lack of natural production of amylin and/or deposition or accumulation of extracellular amyloid fibers, which contribute to the dysfunction or failure of systemic organs such as the pancreas or the brain.
