Martin LEFKOWITZ;Victor Chengwei SHI;Toni Lynne Bransford;Thomas LANGENICKEL;Bryan BURKEY
发明人:
Toni Lynne Bransford,Bryan BURKEY,Thomas LANGENICKEL,Martin LEFKOWITZ,Victor Chengwei SHI
申请号：
US14914029
公开号：
US20160206597A1
申请日:
2013.08.26
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to methods and pharmaceutical compositions for renal protection in a mammal in need thereof, such as a mammal having a disease manifested by atrial enlargement and/or remodeling or suffering from hypertension or heart failure or being prone to suffering from hypertension and/or heart failure, comprising administration of a therapeutically effective amount, or a prophylactically effective amount, of an Angiotensin Receptor Neprilysin inhibitor (ARNi) or of a combination of an Angiotensin Receptor Blocker (ARB) with a Neutral Endopeptidase inhibitor (NEPi) or with a NEPi pro-drug to said mammal.
