The invention relates to antibodies and binding fragments thereof that are capable of binding to influenza A virus hemagglutinin and neutralizing at least one group 1 subtype and at least 1 group 2 subtype of influenza A virus.本發明係關於能夠結合至流感A病毒血球凝集素且中和流感A病毒之至少一個第1群亞型及至少1個第2群亞型之抗體及其結合片段。