DÉRIVÉS D'IMIDAZOLIN-5-ONE UTILES EN TANT QU'INHIBITEURS DE FASN POUR LE TRAITEMENT DU CANCER

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专利权人:

Janssen Pharmaceutica NV

发明人:

申请号：

EP14824671.3

公开号：

EP3083600B1

申请日:

2014.12.15

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention is directed to imidazolin-5-one derivatives, pharmaceutical compositions containing them, and their use as FASN inhibitors, in for example, the treatment of cancer, obesity related disorders, and liver related disorders. Such compounds are represented by formula (I) as follows: wherein R1, R2, R3, R4, R5, m, n, and are defined herein.

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