A method for monitoring the seating of a guide catheter during a catheter procedure includes monitoring at least one parameter of the catheter procedure and determining if the at least one parameter indicates that a guide catheter is out of position. If the at least one parameter indicates the guide catheter is out of position, an alert is displayed and the position of the guide catheter is adjusted. The parameter may be, for example, blood pressure, an ST wave of an electrocardiogram, contrast agent, fluoroscopic images of a region including the distal end of the guide catheter and ultrasound signals.
