Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers
- 专利权人:
- Hong Zhao
- 发明人:
- Hong Zhao,Maria Belen Rubio,Dechun Wu,Puja Sapra
- 申请号：
- US12762434
- 公开号：
- US08299089B2
- 申请日:
- 2010.04.19
- 申请国别(地区):
- US
- 年份:
- 2012
- 代理人:
- 摘要：
- A four arm-polyethylene glycol-7-ethyl-10-hydroxycamptothecin conjugate, such as,is disclosed. Methods of making the conjugates and methods of treating mammals using the same are also disclosed.
- 来源网站：
- 中国工程科技知识中心
相关发明人
相关专利
- Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers
- Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers
- TREATMENT OF RESISTANT OR REFRACTIONAL CANCERS WITH 7-ETIL-10-HYDROXYCAMPTOTECIN MULTI-ARM POLYMERIC CONJUGATE
- Methods of treating HER2 positive cancer with HER2 receptor antagonist in combination with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin
- Treatment of resistant or refractory cancers with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin
