AMOGREENTECH CO., LTD.;KANGWON NATIONAL UNIVERSITY UNIVERSITY-INDUSTRY COOPERATION FOUNDATION
发明人:
Kwon-Soo Ha,Young-Cheol Lim
申请号:
US13987544
公开号:
US20140128323A1
申请日:
2013.08.06
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed are a method and a composition for the prevention or treatment of diabetic angiogenesis impairment or diabetic wound-healing impairment, using C-peptide. Found to be able to induce angiogenesis through chemotatic migration of endothelial cells, cell migration to wounded areas, capillary-like network formation, and ERK1/2 and Akt phosphorylation and NO production, C-peptide has prophylactic or therapeutic applications in a broad spectrum of various diabetic complications including diabetic angiogenesis impairment.