INC.;CONOR MEDSYSTEMS;CONOR MEDSYSTEMS, INC.;SHANLEY, JOHN F.
发明人:
LITVACK, FRANK,PARKER, THEODORE L.,SHANLEY, JOHN F.
申请号:
CA2513721
公开号:
CA2513721C
申请日:
2003.11.10
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
A method and apparatus for the local delivery of therapeutic agents reducesmyocardial tissue damage due to ischemia. A local delivery device is used fordelivery of the therapeutic agents into a coronary artery which feeds theischemic myocardial tissue. According to one example, an implantable medicaldevice for delivering insulin locally to myocardial tissue includes atherapeutic dosage of insulin in a biocompatible polymer affixed to a stent.The therapeutic dosage of insulin is released from the stent at a therapeuticdosage and over an administration period effective to reduce ischemic injuryof the myocardial tissue.