Alice L. Yu,Wen-Der Lin,Jung-Tung Hung,Tan-Chi Fan
申请号：
US15667067
公开号：
US20180037909A1
申请日:
2017.08.02
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to modified cancer cell lines, wherein the ST3Gal1 glycosyltransferase expression is reduced or inhibited. The use of the modified cancer cell lines with suppressed ST3Gal1 glycosyltransferase to screen a potential cancer therapeutic is provided. The suppression of ST3Gal1 glycosyltransferase expression, with or without an anti-cancer agent is also provided to inhibit the growth of cancer cells in a subject.
