Jacob Nielsen;Morten Langgård;Jan Kehler;John Paul Kilburn;Ask Püschl;Mauro Marigo
发明人:
Ask Püschl,Jacob Nielsen,Jan Kehler,John Paul Kilburn,Mauro Marigo,Morten Langgård
申请号：
US13515325
公开号：
US08501797B2
申请日:
2010.12.15
申请国别(地区):
US
年份:
2013
代理人:
摘要：
This invention is directed to compounds of formula I having the structurewhich are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.
