The invention relates to (hetero)cyclic compounds as S1P modulators, pharmaceutical compositions comprising such compounds, and uses thereof in the treatment, alleviation or prevention of diseases or disorders mediated by an S1P receptor.本發明關於作為S1P調節劑的(雜)環化合物、包含此類化合物的藥學組成物、及其用於治療、緩解或預防由S1P受體所中介的疾病或病症之用途。