The Broad Institute, Inc.; Inc.;The Brigham and Women's Hospital, Inc.;President and Fellows of Harvard College;Massachusetts Institute of Technology;The Brigham and Womens Hospital
发明人:
Regev, Aviv,Kuchroo, Vijay,Park, Hongkun,Yosef, Nir,Shalek, Alexander K.,Gaublomme, Jellert,Joller, Nicole C.,Wu, Chuan,Anderson, Ana Carrizosa
申请号:
AU2014223344
公开号:
AU2014223344A1
申请日:
2014.02.27
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
This invention relates generally to compositions and methods for identifying the regulatory network that modulates, controls or otherwise influences T cell balance, for example, Thl7 cell differentiation, maintenance and/or function, as well compositions and methods for exploiting the regulatory network that modulates, controls or otherwise influences T cell balance in a variety of therapeutic and/or diagnostic indications. This invention also relates generally to identifying and exploiting target genes and/or target gene products that modulate, control or otherwise influence T cell balance in a variety of therapeutic and/or diagnostic indications.