A left atrial appendage occluder (10, 20, 30, 40, 50) and a fabricating method thereof are provided. The left atrial appendage occluder (10, 20, 30, 40, 50) includes a plugging column (11) and a anchor (12) located on the plugging column (11), wherein the plugging column (11) is woven from an elastic metal wire (18), or woven from an elastic metal wire (18) and an elastic metal sheet (21), the anchor (12) is made by partially flattening and then cutting the elastic metal wire (18), or the anchor (12) is made by cutting the elastic metal sheet (21). In the above-described left atrial appendage occluder (10, 20, 30, 40, 50), firstly, the anchor (12) is formed on the elastic metal wire (18) and/or the elastic metal sheet (21), and then the elastic metal wire and/or the elastic metal sheet (21) with the anchor (12) are/is co-woven with other elastic metal wire (18) to form the plugging column (11) of the left atrial appendage occluder (10, 20, 30, 40, 50). Therefore, the amount of the anchor (12) is not limited, and a plurality of anchors can be provided, so that after the left atrial appendage occluder (10, 20, 30, 40, 50) is implanted in a human body, pressure of a tip of the anchor (12) is smaller, damage to the left atrial appendage is smaller, a fitting property between the left atrial appendage occluder (10, 20, 30, 40, 50) and the left atrial appendage is improved, meanwhile support force of the plugging column (11) is also improved, and the structural strength of the left atrial appendage occluder (10, 20, 30, 40, 50) is ensured to meet the actual demand.
