SUDA Yumiko,SAKAI Toshiro,KOJIMA Ryo,OYAMA Dai,NISHIMURA Koji,NAIKI Kumi
申请号：
PH12017501831
公开号：
PH12017501831A1
申请日:
2017.10.06
申请国别(地区):
PH
年份:
2018
代理人:
摘要：
Disclosed is a pharmaceutical composition for oral administration, comprising 1-{5-[(5-{[(2R)-2-ethylpyrrolidin-1-yl]methyl}-4-[4- methoxy-3-(trifluoromethyl)phenyl]-1,3-thiazol-2- yl)carbamoyl]pyrazin-2-yl}piperidine-4-carboxylic acid, which is a compound having pH-dependent solubility, or a pharmaceutically acceptable salt thereof and a cellulose derivative. In the pharmaceutical composition for oral administration, the solubility and absorbability of the medicinal substance are improved.
