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REACTIONS TRIGGERED BY COOLING-INDUCED GEL-TO-SOL TRANSITION OF THERMORESPONSIVE POLYMERS
专利权人:
Vanderbilt University
发明人:
Leon M. Bellan
申请号:
US16653883
公开号:
US20200113816A1
申请日:
2019.10.15
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided are pharmaceutical compositions, which include a gel comprising a thermoresponsive polymer, the polymer being soluble in water at a temperature of 37° C. or lower; and a therapeutic compound, or a pharmaceutically acceptable salt thereof, dispersed in the gel. Also provided are methods of delivering a therapeutic compound, which include administering the disclosed pharmaceutical composition to a subject in need thereof (e.g., by subcutaneous administration).
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