DRAGET KURT INGAR,HAUG INGVILD,HATTREM MAGNUS N,SETERNES TORE,ENGELSEN STEINAR JOHAN
申请号:
IN9351/DELNP/2012
公开号:
IN2012DN09351A
申请日:
2012.10.29
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
The invention provides an oral pharmaceutical composition optionally in dose unit form comprising a lipophilic drug substance in dispersion in a physiologically tolerable aqueous carrier preferably an aqueous gel wherein said drug substance contains a functional electrostatic group having a pKa value of from 2 to 10 characterised in that said aqueous carrier has a pH at least 0.3 below or above said pKa value said pH being below said pKa where said group is acidic and above said pKa where said group is basic.