Systems, computer-readable media, and methods for assessing morphometric measures of spinal vertebrae and inter-vertebral discs in a quantitative manner using imaging data and human body weight measures, for identification and prediction of structural spine pain, are described. The systems, media, and methods of the present disclosure utilize simple measurements of axial areas of vertebrae using endplate data of routinely acquired digital imaging pixels and body weight. More specifically, they provide a calculation pressure value based on one or more ratios from body weight and measurements of spinal structures and regions, which are readily determinable, e.g., through manual segmenting or automated programming of image analysis software.