Devices are disclosed that can be used with a medical instrument that comprises an elongated sheath and a hub that comprises a sideport. The hub and the sheath of the medical instrument are configured to permit at least a portion of an elongated medical implement to pass through them. The devices can include a plurality of engagement members that cooperate to define an opening through which the elongated medical implement can pass and a biasing surface. The devices can further include an adapter that includes an attachment mechanism to directly engage the sideport to secure the adapter to the medical instrument and a locking member for coupling with the adapter. The adapter and the locking member can interact to advance the plurality of engagement members along the biasing surface to transition the engagement members from an open state to a locked state.