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USE OF DERMATOPONTIN FOR MAINTAINING HEMATOPOIETIC STEM AND/OR PROGENITOR CELLS IN CULTURE
专利权人:
发明人:
申请号:
EP16751268.0
公开号:
EP3331993A1
申请日:
2016.08.05
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention relates to the use of dermatopontin (DPT) or a functional fragment thereof for the maintenance of hematopoietic stem and/or progenitor cells in culture. The present invention further relates to a method for maintaining hematopoietic stem and/or progenitor cells in culture, the method comprising culturing the hematopoietic stem and/or progenitor cells in the presence of dermatopontin (DPT) or a functional fragment thereof. Furthermore, the present invention relates to a cell culture medium for the maintenance of hematopoietic stem and/or progenitor cells, wherein the cell culture medium comprises a medium and dermatopontin (DPT) or a functional fragment thereof and further optionally comprises serum/serum replacement, (a) reducing agent(s), and/or (an) antibiotic(s) as well as a kit comprising dermatopontin (DPT) or a functional fragment thereof and at least one of: (a) (a) cell culture medium (b) one or more cytokines (c) serum/serum replacement (d) (a) reducing agent(s), and/or (e) (an) antibiotic(s).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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