Eric R. Prossnitz,Geetanjali Sharma,Matthias Barton,Matthias R. Meyer
申请号：
US16577661
公开号：
US20200113875A1
申请日:
2019.09.20
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The current invention is in the field of molecular biology/pharmacology and provides methods of using compounds that modulate the effects of GPR30/GPER for treating obesity and diabetes (preferably agonists) as well as disease states and/or conditions that result from excessive formation of reactive oxygen species (preferably antagonists). These compounds may function as agonists and/or antagonists of the disclosed estrogen receptor and/or modulate the expression/upregulation of nox and nox-associated reactive oxygen species (ROS).
