ANTI-INFLAMMATORY, SKIN-REGENERATIVE, WHITENING, ANTIOXIDANT, OR WOUND-HEALING COMPOSITION CONTAINING CULTURE MEDIUM OF ADSC-T CELLS IN WHICH T-ANTIGEN IS INTRODUCED INTO ADIPOSE-DERIVED STEM CELL AS ACTIVE INGREDIENT
Changwon National University Industry Academy Cooperation Corps
发明人:
Dongwan KIM,Han N. PARK,Gyu B. KIM
申请号：
US14785265
公开号：
US20160074499A1
申请日:
2013.08.29
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to an anti-inflammatory, skin-regenerative, whitening, antioxidant, or wound-healing composition containing a culture medium of adipose-derived stem cell-T (ADSC-T) cells as an active ingredient, in which T-antigen is introduced into an adipose-derived stem cell. The culture medium of ADSC-T cells, according to the present invention, has remarkable effects for treating or inhibiting inflammation by alleviating atopic dermatitis, which is an autoimmune disease, and inhibiting NF-κB activities through an increase of an Iκbα expression. Additionally, the culture medium, according to the present invention, exhibits: excellent skin regenerative effects by having effects of enhancing skin collagen elasticity and reducing wounds, in a collagen culture； excellent skin whitening effects by inhibiting tyrosinase activities and melanin production； and excellent anti-oxidation effects by inhibiting DPPH radical activities. Furthermore, the present invention has remarkable wound-healing effects by enhancing cell mobility of fibroblast, and is thus useful for anti-inflammation, skin-regeneration, whitening, anti-oxidation, or healing wounds.
