Provided herein are pharmaceutical compositions comprising Eteplirsen. Also provided herein are methods of treating a muscle disease in a subject in need thereof, comprising administering to the subject a pharmaceutical composition of the disclosure.本文所提供係包含依替利森(Eteplirsen)之醫藥組合物。本文另外提供治療有需要之個體之肌肉疾病之方法,該方法包含向該個體投與本揭示內容之醫藥組合物。