Gregory P. Chang,Ann F. Cheung,William Haney,Bradley M. Lunde,Bianka Prinz
申请号：
US16483572
公开号：
US20200095327A1
申请日:
2018.02.08
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Antibody heavy chain variable domains that can be paired with any of a variety of antibody light chain variable domains to form an antigen binding site targeting the NKG2D receptor on natural killer cells are described. Also described are antibodies and antigen-binding sites that compete for binding to NKG2D. Related pharmaceutical compositions and therapeutic methods, including for the treatment of cancer, are also described.
