Indiana University Research and Technology Corporation
发明人:
Mervin C. Yoder,David P. Basile
申请号:
US16311633
公开号:
US20190388477A1
申请日:
2018.02.21
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure provides compositions and methods for the treatment or prophylaxis of a perfusion disorder, such as ischemia and/or reperfusion injury, in a subject's organ, tissue or extremity by preserving or improving endothelial function, reducing vascular injury, and/or promoting vascular repair. The disclosed compositions comprise endothelial colony-forming cells or a serum-free composition comprising chemically defined media conditioned by endothelial colony-forming cells.