Willems, Hendrika Maria Gerarda,Kallblad, Per,Hardcastele, Ian Robert,Griffin, Roger John,Golding, Bernard Thomas,Lunec, John,Nobel, Martin E. M.,Newell, David R.,Calvert, Alan H.
申请号：
AU2005278962
公开号：
AU2005278962C1
申请日:
2005.08.26
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
A compound of formula (1) or a prodrug and/or pharmaceutically acceptable salt thereof,wherein X is selected from O, N or S； R is selected from hydrogen, halo,hydroxy, substituted or unsubstituted alkyl, substituted or unsubstituted hydroxyalkyl,substituted or unsubstituted alkylamine, alkoxy, substituted or unsubstitutedaryl or heteroaryl, and substituted or unsubstituted aralkyl or heteroaralkyl；R is selected from hydrogen, halo, hydroxy, substituted or unsubstitutedalkyl, substituted or unsubstituted hydroxyalkyl substituted or unsubstitutedalkylamine, alkoxy, substituted or unsubstituted aryl or heteroaryl, and substitutedor unsubstituted aralkyl or heteroalkyl； R is selected from hydrogen,halo, hydroxy, substituted or unsubstituted alloy substituted or unsubstitutedhydroxyalkyl, substituted or unsubstituted alkylamine alkoxy, substitutedor unsubstituted aryl or heteroaryl, and substituted or unsubstituted aralkylor heteroalkyl； and R-R, is used to represent groups R,R, R and R which are independently selectedfrom H, OH, alkyl, alkoxy, alkylamine, hydroxyalkyl, halo, CF, NH,NO, COOH, C=0.
