A fluid reservoir for use with a drug delivery device comprises a sealed fluid chamber (58) having a top surface (50) and a bottom surface (52), and a cavity (58) therebetween. The cavity (58) is at least partially defined by at least one seal (54, 56), the cavity (58) serving to house a fluid therein. Means (62) for fracturing at least a portion (66) of the at least one seal (54, 56) and means (68) for controllably releasing a liquid, positionable within the cavity (58), out of the cavity (58) are provided.