Compounds modulators of VEGF activity and uses thereof

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专利权人:

发明人:

Luca Domenico DAndrea,Carlo Pedone,Maria Caterina Turco

申请号：

US14259085

公开号：

US09737622B2

申请日:

2014.04.22

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Compounds of general formula (1): X1Y1X2Y2X3Y3X4Y4Y5X5X6Y6X7Y7X8X9X10 wherein X1-X10 are any natural or unnatural amino acids and Y1 is Gln Y2 is Met or Leu Y3 is He Y4 is Pro or Ser Y5 is His or Gly Y6 is Gln or Pro Y7 is He or Tyr or their homolog or ortolog are described these compounds are able to bind to the VEGF receptors and to modulate the angiogenesis mediated by the VEG.

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