A vapour provision system comprising: a first activation sensor; a second activation sensor; user programming circuitry configured, in response to user input, to store a first user-defined setting for use in association with the first activation sensor and a second user-defined setting for use in association with the second activation sensor; and power supply control circuitry configured to control a supply of power to a vaporiser to generate vapour from a vapour precursor material for user inhalation, wherein the power supply control circuitry is configured to control the supply of power to the vaporiser in accordance with the first user-defined setting in response to detecting user activation of the first activation sensor and to control the supply of power to the vaporiser in accordance with the second user-defined setting in response to detecting user activation of the second activation sensor.