PROBLEM TO BE SOLVED: To provide a novel pyrimidine nucleoside compound exhibiting more excellent balance of antitumor effect and toxicity than that of existing pyrimidine nucleoside compounds.SOLUTION: The compound is represented by the general formula (1): [in the formula, one of A1 and A2 is a hydrogen atom or a group represented by (R1)(R2)(R3)Si- and the other is a group represented by (R4)(R5)(R6)Si-, or A1 and A2 are taken together to form a cyclic group represented by -(R7)(R8)Si- or -(R9)(R10)Si-O-Si(R11)(R12)- R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 each represents an alkyl group having a carbon number of 1 to 12 which may have a substituent group or an aryl group having a carbon number of 6 to 14 which may have a substituent group].COPYRIGHT: (C)2015,JPO&INPIT【課題】既存のピリミジンヌクレオシド化合物よりも抗腫瘍効果と毒性の優れたバランスを示す、新規なピリミジンヌクレオシド化合物を提供する。【解決手段】下記一般式(1)[式中、A1、A2は、一方が水素原子又は(R1)(R2)(R3)Si-で表される基で、他方が(R4)(R5)(R6)Si-で表される基を示すか、又はA1とA2が一緒になって-(R7)(R8)Si-若しくは-(R9)(R10)Si-O-Si(R11)(R12)-で表される環状基を形成し;R1、R2、R3、R4、R5、R6、R7、R8、R9、R10、R11、及びR12は、置換基を有しても良い炭素数1乃至12のアルキル基、又は置換基を有しても良い炭素数6乃至14のアリール基を示す]【選択図】なし
